What is a typical physical change observed in patients with advanced Alzheimer's disease?

In advanced Alzheimer's disease, patients often experience significant physical changes due to the progression of the disease affecting various bodily functions. One of the more common changes is significant weight loss, which can result from a combination of factors. Patients may have difficulty swallowing, known as dysphagia, which can lead to reduced food intake and subsequent weight loss. Their cognitive decline may also diminish the desire or ability to eat properly, further compounding this issue.

As the disease progresses, it often leads to a decline in motor functions and coordination, rather than improvement. Mobility generally decreases in advanced stages, often leading to increased dependence and a greater risk of falls. The heightened sensory awareness noted in the other options is not a typical characteristic observed in advanced stages of Alzheimer's, as cognitive decline generally leads to decreased awareness and responsiveness to sensory stimuli. Thus, the combination of these factors makes the observation of significant weight loss and difficulty swallowing a typical physical change in advanced Alzheimer's disease.